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From the abstract: Cluster of differentiation 38 (CD38) is a promising therapeutic target in multiple myeloma (MM) patients and has resulted in the development of several CD38 immunotherapies. Current methods to evaluate CD38 expression in the preclinical setting include ex vivo flow cytometry and immunohistochemistry, which can be cumbersome and do not give whole-body information. In vivo imaging technologies […]
From the abstract: The essential G1-cyclin, CCND1, is a collaborative nuclear oncogene that is frequently overexpressed in cancer. D-type cyclins bind and activate CDK4 and CDK6 thereby contributing to G1–S cell-cycle progression. In addition to the nucleus, herein cyclin D1 was also located in the cytoplasmic membrane. In contrast with the nuclear-localized form of cyclin D1 […]
Dr. Achilefu and Dr. Chheda are named Pedal the Cause Featured Fighters for their advancements in cancer treatment thanks in part to funds donated by Pedal the Cause. Join Dr. Achilefu and Dr. Chheda at the Cancer Lasers Team at Pedal the Cause!
Dr. Joe Culver has been installed as the endowed Sherwood Moore Professor of Radiology